The MOPITT (“Measurements of Pollution in the Troposphere”) satellite instrument has been making observations of atmospheric carbon monoxide since 2000. Recent enhancements to the MOPITT retrieval algorithm have resulted in the release of the Version 7 (V7) product. Improvements include (1) representation of growing atmospheric concentrations of N<sub>2</sub>O, (2) use of meteorological fields from the MERRA-2 reanalysis for the entire MOPITT mission (instead of MERRA), (3) use of the MODIS Collection 6 cloud mask product (instead of Collection 5), (4) a new strategy for radiance bias correction, and (5) an improved method for calibrating MOPITT’s NIR radiances. Statistical comparisons of V7 validation results with corresponding V6 results are presented, using aircraft in-situ measurements as the reference. Clear improvements are demonstrated for V7 products with respect to overall retrieval biases, bias variability, and bias drift uncertainty.